Medical and Biotechnological Applications

The growth of the medical technology sector is accompanied by a multitude of innovations. The development of new products and medical devices as well as therapies is often based upon highly complex raw materials. Fraunhofer FEP has been researching and developing technologies for the modification, functionalization, and coating of surfaces for many years. For this we utilize our core competencies in electron beam and plasma technology, precision coating and organic electronics. We are increasingly applying this know-how to medical and biotechnological issues in order to offer innovative solutions, technologies and efficient treatment methods.

In particular, the topics of sterilization, hygienization and inactivation as well as the processing of tissue for transplants have experienced significant growth in depth and breadth. The treatment of biological tissue using low-energy electrons offers a new possibility of non-destructive sterilization and preservation, and is a main focus of our research.

We use our core technologies to apply biofunctional coatings to critical surfaces or make specific changes to their properties, such as increasing the compatibility of implants with the biological environment (biocompatibility). In the field of wound healing, Fraunhofer FEP works with various antimicrobial coatings. Treatment of medical devices with low energy electrons has also proven to be an effective tool for germ reduction and sterilization of packaging, implants and medical devices.
In our biomedical laboratory unit, we can directly test treated surfaces for biocompatibility and degree of sterilization. In the inactivation of viruses for vaccine production, we are pursuing the replacement of chemistry-based methods with electron beam treatment. This is faster and at the same time more gentle on the vaccine sera, so that more effective vaccines can be produced in a short time.

In addition, research is being conducted on the use of organic light-emitting diodes (OLEDs) for use in light therapy or cell stimulation, for example. Since 2019, our research activities have been addressing the emerging topics of biotechnological processes, exploring the combination of traditional core competencies of the institute with novel bioreactor systems for a wide range of applications.

Let us find together a suitable solution for your medical or biotechnological applications. We look forward to hearing from you!

Fraunhofer FEP offers comprehensive competencies with regard to the development and improvement of technologies for medical applications along the entire value-added chain:

• Customized feasibility studies
• Conceptualization and planning of an R&D project complete with PM work packages, milestones, and costing
  
• Technology development of coating solutions for medical applications
  Development of biofunctional coatings
• Development of surface modification by treatment with low-energy electrons, UV or plasma
• Development of associated systems (e.g. compact sterilizers as in-line system solutions, batch/benchtop systems or end-of-pipe sterilization, e.g. using low-energy electrons)
• Proof-of-concept e.g. of disinfection and sterilization processes
  Portable and integratable monitoring systems based on OLED or microdisplay technology
• Evaluation of the bacterial load of processes and products/materials
  Verified microbiological and cell biological test laboratory
• Closed development chains incl. clinical trials through existing cooperations
• Cleaning know-how from condition analysis and training to the development of customized cleaning technologies
• Technology transfer
  

This development work is augmented and supported by:

• Acquisition and coordination of projects funded by the state and federal governments as well as by the European Union
  
• Economic viabilitiy studies
• Studies on the state of the art, e.g. literature and patent searches